1,1-ETHANEDIOL, 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUORO-, HYDROCHLORIDE - Names and Identifiers
Name | 2'-Amino-5'-chloro-2,2,2-trifluoroacetophenone
|
Synonyms | 214353-17-0 2-TRIFLUOROACETYL-4-CHLORO ANILINE 2-Amino-5-chlorophenyl-2,2,2-trifluoroethanone 2'-Amino-5'-chloro-2,2,2-trifluoroacetophenone 2'-AMINO-5'-CHLORO-2,2,2-TRIFLUOROACETOPHENONE 2-AMINO-5-CHLORO-2',2',2'-TRIFLUOROACETOPHENONE 4-Chloro-2-trifluoroacetoaniline hydrochloride hydrate 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diol 4-chloro-2-(2,2,2-trifluoro-1,1-dihydroxyethyl)anilinium chloride 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diol hydrochloride 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride 1,1-ETHANEDIOL, 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUORO-, HYDROCHLORIDE 4-Chloro-2-Trifluoroaceto Aniline Hydrochloride Hydrate (The Intermediate Of Efavirenz)
|
CAS | 214353-17-0
|
EINECS | 433-580-2 |
InChI | InChI=1/C8H7ClF3NO2/c9-4-1-2-6(13)5(3-4)7(14,15)8(10,11)12/h1-3,14-15H,13H2 |
1,1-ETHANEDIOL, 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUORO-, HYDROCHLORIDE - Physico-chemical Properties
Molecular Formula | C8H5ClF3NO
|
Molar Mass | 223.58 |
Density | 1.624g/cm3 |
Boling Point | 381.771°C at 760 mmHg |
Flash Point | 184.689°C |
Vapor Presure | 0mmHg at 25°C |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.559 |
1,1-ETHANEDIOL, 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUORO-, HYDROCHLORIDE - Introduction
2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone is an organic compound with the chemical formula C8H6ClF3NO. Its properties are as follows:
1. Appearance: 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone is colorless to light yellow crystal or powder.
2. Solubility: It can be dissolved in some organic solvents, such as ethanol, dimethyl ether and chloroform, but it is insoluble in water.
3. Use: 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone is commonly used in organic synthesis, as a reagent or intermediate. It can be used to synthesize other organic compounds, such as dyes, pesticides and drugs.
4. Preparation method: A commonly used synthesis method is to prepare 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone by chlorination of para-diaminophenone. A specific method includes the reaction of p-diaminobenzophenone with thionyl chloride and lithium aluminum thionyl chloride in an organic solvent.
5. Safety Information: 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone should pay attention to safety during use. It may be irritating to the eyes, skin and respiratory system. Use appropriate protective equipment such as chemical goggles, gloves and masks. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help. When storing and handling the compound, the appropriate safety procedures should be observed.
Last Update:2024-04-09 15:17:55